GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7267979 | 1 | rs4815409 | chr20:25346697 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.23 | 1.88E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815409 | chr20:25346697 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.49 | 0.000536 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815409 | chr20:25346697 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.4 | 1.06E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815409 | chr20:25346697 | NINL | chr20:25433338-25566153:- | 0.33 | 6.9 | 1.7E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815409 | chr20:25346697 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.03 | 6.5E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815411 | chr20:25350223 | ENTPD6 | chr20:25176339-25207360:+ | 0.31 | 7.11 | 4.23E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815411 | chr20:25350223 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.46 | 0.000585 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815411 | chr20:25350223 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.45 | 8.06E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815411 | chr20:25350223 | NINL | chr20:25433338-25566153:- | 0.34 | 7.08 | 5.02E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815411 | chr20:25350223 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.08 | 5.35E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815412 | chr20:25350325 | ENTPD6 | chr20:25176339-25207360:+ | -0.32 | -7.44 | 4.84E-13 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815412 | chr20:25350325 | FAM182A | chr20:26035250-26067552:+ | -0.2 | -3.71 | 0.000231 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815412 | chr20:25350325 | FAM182B | chr20:25744102-25848786:- | 0.25 | 5.21 | 2.82E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815412 | chr20:25350325 | NINL | chr20:25433338-25566153:- | -0.34 | -7.05 | 6.18E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815412 | chr20:25350325 | PYGB | chr20:25228706-25278647:+ | -0.15 | -3.74 | 0.000209 | Liver enzyme levels (alkaline phosphatase) |